Tandem mass spectra of ammonium adducts of monosaccharides: differentiation of diastereomers |
| |
Authors: | Madhusudanan K P |
| |
Institution: | Sophisticated Analytical Instrument Facility, Central Drug Research Institute, Lucknow-226001, India. kpmadhusudanan@hotmail.com |
| |
Abstract: | Tandem mass spectra of ammonium adducts of monosaccharides gave characteristic fragmentation patterns involving elimination of NH3/H2O followed by multiple eliminations of H2O and cross ring cleavages. Tandem mass spectra were examined over a range of collision energies (1-20 eV) on a triple-quadrupole mass spectrometer. The breakdown behavior of the ammonium adducts revealed patterns that could differentiate diastereomers of monosaccharides. |
| |
Keywords: | MS/MS spectra ammonium adducts electrospray ionization monosaccharides differentiation of diastereomers |
本文献已被 PubMed 等数据库收录! |