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Stereoselective synthesis of β-carboethoxy-γ-lactams via imino Mukaiyama aldol-type reaction of 1,4-bis(trimethylsilyloxy)-1,4-diethoxy-1,3-butadiene
Authors:Manat Pohmakotr
Affiliation:Department of Chemistry, Faculty of Science, Mahidol University, Rama 6 Road, Bangkok 10400, Thailand
Abstract:The reaction of the (bis)trimethylsilyloxy derivative of diethyl succinate with imines in the presence of ZnCl2 provides a general stereoselective entry to β-carboethoxy-γ-lactams.
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