Synthesis and transformations of 4-hydroxy-5-methyl-2-trifluoromethylpyridine

4-Hydroxy-5-methyl-2-trifluoromethylpyridine was synthesized from 3-hydroxy-3-methyl-6-trifluoromethyl-2,3-dihydro-4H-pyran-4-one. Its methylation leads to the formation of a mixture of N- and O-alkylation products, which were isolated chromatographically in the pure state. Convenient methods of their preparation are proposed.Belorussian State University, Minsk 220050. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 780–784, June, 1998.