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Synthesis of isatin-conjugated 3H-indole-N-oxides and their serendipitous conversion to spiroindolenines
Authors:Hwa Jung Roh  Gieun Kim  Sung Cho  Ji Yeon Ryu  Junseong Lee  Jae Nyoung Kim
Institution:Department of Chemistry and Institute of Basic Science, Chonnam National University, Gwangju 500-757, Republic of Korea
Abstract:Isatin-conjugated 3H-indole-N-oxides were synthesized from isatin-derived propargylic alcohols and nitrosobenzenes in moderate yields. Isatin-conjugated 3H-indole-N-oxides were converted to novel spiroindolenines under PPh3-mediated deoxygenation reaction condition, serendipitously.
Keywords:Nitrosobenzenes  Propargylic alcohols  Spiroindolenines
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