A dual-response naphthofluorescein-based fluorescent probe for multiple-channel imaging of cysteine/homocysteine in living cells |
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| Authors: | Xiuxiu Yue Wenxiu Li Wenqiang Chen Liangliang Zhang Guofang Li Jiarong Sheng |
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| Affiliation: | 1. College of Chemistry and Materials Science, Guangxi Teachers Education University, 530001 Nanning, Guangxi, PR China;2. Guangxi Key Laboratory of Natural Polymer Chemistry and Physics (Guangxi Teachers Education University), Nanning 530001, PR China;3. State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources of Education Ministry, Guangxi Normal University, 541004 Guilin, Guangxi, PR China |
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| Abstract: | A naphthofluorescein-based fluorescent probe with two independent reaction sites (nitro-2,1,3-benzoxadiazole and acrylate moiety) was developed. Integrating these two reaction sites into a single molecule not only can guarantee the selective detection of Cys/Hcy in an elegant fashion, but also can enable Cys/Hcy detection in a multiple-channel responsive manner. |
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| Keywords: | Fluorescent probe Naphthofluorescein-based Cysteine (Cys) Homocysteine (Hcy) |
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