Dehydrogenative etherification homocoupling of heterocyclic N-oxides |
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Authors: | Dong Zhang Kai Qiao Xin Yuan Mingwei Zheng Zheng Fang Li Wan Kai Guo |
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Affiliation: | 1. College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, 30 Puzhu South Road, Nanjing 211816, China;2. State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, 30 Puzhu South Road, Nanjing 211816, China |
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Abstract: | A novel approach was developed for the dehydrogenative etherification homocoupling of heterocyclic N-oxides in the presence of silver oxide and PyBroP. Various substrates were well tolerated and the desired products were obtained in moderate to good yields. Generally, this reaction features excellent functional group compatibility, broad substrate scope and good regioselectivity. |
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Keywords: | Regioselective Homocoupling Quinoline PyBroP Corresponding authors at: College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, 30 Puzhu South Road, Nanjing 211816, China. |
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