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Copper-catalyzed radical oxytrifluoromethylation of alkenyl oximes at ambient temperature |
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| Authors: | Xi-Tao Li Ling Lv Qiang-Shuai Gu Xin-Yuan Liu |
| Affiliation: | 1. Department of Chemistry and Shenzhen Grubbs Institute, Southern University of Science and Technology, Shenzhen, 518055, China;2. Academy for Advanced Interdisciplinary Studies, Southern University of Science and Technology, Shenzhen, 518055, China |
| Abstract: | A mild and efficient copper-catalyzed radical oxytrifluoromethylation reaction of alkenyl oximes was successfully developed. The method provides a straightforward access to a wide range of CF3-containing isoxazolines in good to excellent yields. |
| Keywords: | Alkenyl oximes Copper catalysis Isoxazolines Radical oxytrifluoromethylation |
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