A general synthesis of the acarnidines |
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| Authors: | John W Blunt Murray HG Munro Selwyn C Yorke |
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| Institution: | Chemistry Department, University of Canterbury, Christchurch, New Zealand |
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| Abstract: | A general synthetic route to the biologically active marine natural products, the acarnidines (10a–c),1 and bolecules of the acarnidine type, is presented. The substituted homospermidine skeleton of the acarnidines was synthesised via an aldimine intermediate prepared from mono-BOC protected 1,5-diaminopentane (5) and the aldehyde (4). |
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