Synthesis of binzindene prostaglandins: a novel potent class of stable prostacyclin analogs |
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Authors: | Paul A Aristoff Allen W Harrison |
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Institution: | Experimental Chemistry Research The Upjohn Company Kalamazoo, Michigan 49001 U.S.A. |
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Abstract: | The phenols , , and , produced with remarkable regioselectivity by the cyclization of compounds and , have been converted to the benzindene prostaglandin analogs , , and , respectively. Compounds and are potent prostacyclin mimics. |
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Keywords: | |
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