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A new general method of α-amino-alkylation |
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| Authors: | J Morton A Rahim ERH Walker |
| Institution: | ICI Pharmaceuticals Division, Alderley Park, Mereside, Macclesfield, Cheshire England |
| Abstract: | N-(1-p-Toluenesulphonyl-alkyl) amides, which are readily prepared from a aldehyde, an amide and sodium p-toluenesulphinate, are versatile α-amido-alkylating agents for sulphur nitrogen and carbon nucleophiles. |
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