Synthesis of 2-alkyl(aryl,hetaryl)-4-methyl-1,2,3,4-tetrahydroquinolines |
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Authors: | V. V. Kuznetsov A. É. Aliev N. S. Prostakov |
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Affiliation: | (1) Russian University of National Friendship, 117923 Moscow |
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Abstract: | We have developed a preparative, three stage of synthesis of substituted 1,2,3,4-tetrahydroquinolines. Treatment of N-aryl-imines with allylmagnesium bormide gave N-aryl-N-alkenylamines which were cyclized to the tetrahydroquinolines. The configurations and conformations of the 4-methyl-1,2,3,4-tetra-hydroquinolines containing different 2- substituents have been determined.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 73–78, January, 1994. |
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