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A Facile and Simple Synthesis of Novel 2‐(substituted)‐5‐(1‐methyl‐1H‐indazol‐3‐yl)‐Oxazole Derivatives
Authors:E Vishnu Vardhan Reddy  J Ramanatham  N Devanna  K Srinivasa Reddy  D Rajender
Institution:1. Custom Pharmaceutical Services, Dr Reddys Laboratories Limited, , Miyapur, Hyderabad, India;2. Department of Chemistry, JNT University, , Ananthapur, Andhra Pradesh, India;3. Pfizer Pharmaceuticals India Pvt. Ltd, , Turbhe, Navi Mumbai, India, 400705
Abstract:Novel 2‐(substituted)‐5‐(1‐methyl‐1H‐indazol‐3‐yl)‐oxazoles ( 13 ) were synthesized in moderate yields, from 1‐methyl‐1H‐Indazole 3‐carboxylic acid ( 1 ), by converting it into a variety of amides ( 12 ) and further its heterocyclization. The structures of all the compounds have been elucidated on the basis of IR, 1H‐NMR, and HRMS.
Keywords:
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