Synthesis and Biological Evaluation of Novel Benzoxaboroles as Potential Antimicrobial and Anticancer Agents |
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| Authors: | J. Sravan Kumar M. A. Alam Shirisha Gurrapu Grady Nelson Michael Williams Michael A. Corsello Joseph L. Johnson Subash C. Jonnalagadda Venkatram R. Mereddy |
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| Affiliation: | 1. Department of Chemistry and Biochemistry, University of Minnesota Duluth, , Duluth, Minnesota, 55812 USA;2. Department of Chemistry and Biochemistry, Rowan University, , Glassboro, New Jersey, 08028 USA |
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| Abstract: | Several novel benzoxaborole derivatives were synthesized starting from 2‐formylphenylboronic acid utilizing Baylis–Hillman reaction, Barbier allylation, Passerini reaction, and aldol reaction protocols as the key step. All the synthesized benzoxaboroles have been evaluated for their antibacterial, antifungal, and anticancer activities. |
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