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Synthesis of Epigoitrin from (R)‐(+)‐4‐Hydroxy‐γ‐butyrolactone
Authors:Wei Yin  Chunhua Qiao
Institution:College of Pharmaceutical Science, Soochow University, , Suzhou, 215123 China
Abstract:Epigoitrin is one of the major components of several natural species, including Isatis indigotica Fort, turnip, and cabbage. It presents antithyroid and antivirus activities. Here, we report an efficient and practical method for the chemical synthesis of epigoitrin from commercially available (R)‐(+)‐4‐hydroxy‐γ‐butyrolactone.
Keywords:epigoitrin  chemical synthesis  antiviral  antithyroid
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