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Simple and Efficient Method for the Synthesis of Highly Substituted Imidazoles Catalyzed by Benzotriazole
Authors:Feng Xu  Nige Wang  Youping Tian  Gaoqiang Li
Affiliation:Key Laboratory of Macromolecular Science of Shaanxi Province, School of Chemistry and Chemical Engineering Science, Shaanxi Normal University, , Xi'an, Shaanxi, 710062 People's Republic of China
Abstract:Benzotriazole is an efficient, readily available, and simple catalyst for the synthesis of 2,4,5‐trisubstituted imidazoles in high yields from 1,2‐diketones and aldehydes in the presence of NH4OAc via multi‐components reaction. The significant features of this one‐pot procedure are very simple operation, easy work‐up and purification of products.
Keywords:
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