Pd‐Assisted Cross‐Coupling Reactions with 4‐Chlorocinnoline |
| |
| Authors: | Helmut Julian Heiter Gyte Vilkauskaite Wolfgang Holzer |
| |
| Affiliation: | Department of Drug and Natural Product Synthesis, Faculty of Life Sciences, University of Vienna, , A‐1090 Vienna, Austria |
| |
| Abstract: | A series of 4‐ethynylcinnolines 3a – e was prepared by Sonogashira reaction of 4‐chlorocinnoline ( 1 ) with appropriate alkynes. Moreover, Suzuki coupling of 1 with boronic esters gave the corresponding 4‐arylcinnolines 5a – c . Detailed NMR spectroscopic data including unambiguous chemical shift assignments of all 1H, 13C, and 15N resonances of the obtained cinnoline derivatives are reported. |
| |
| Keywords: | |
|
|
