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Biomimetic Aggrecan Reduces Cartilage Extracellular Matrix From Degradation and Lowers Catabolic Activity in Ex Vivo and In Vivo Models
Authors:Shaili Sharma  Aeju Lee  Kuiwon Choi  Kwangmeyung Kim  Inchan Youn  Stephen B. Trippel  Alyssa Panitch
Affiliation:1. Weldon School of Biomedical Engineering, Purdue University, , West Lafayette, IN, 47907;2. Biomedical Research Institute, Korea Institute of Science and Technology, , Seoul, South Korea;3. College of Medicine, Korea University, , Seoul, South Korea;4. Department of Orthopaedic Surgery, Indiana University School of Medicine
Abstract:
Keywords:aggrecan  biomimetics  cartilage  extracellular matrix  proteolytic enzymes
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