Synthesis and Antitumor Activity of New Substituted Mercapto‐1,2,4‐Triazine Derivatives,Their Thioglycosides,and Acyclic Thioglycoside Analogs |
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Authors: | Ibrahim F Nassar |
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Institution: | Faculty of Education, Ain Shams University, , Cairo, Egypt |
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Abstract: | New 1,2,4‐triazine and their derived thioglycoside derivatives were synthesized from 5,6‐diphenyl‐1,2,4‐triazine‐3‐thiol. Furthermore, the corresponding acyclic thioglycoside analogs were synthesized from the corresponding mercapto derivatives and acyclic oxygenated alkyl halides. The newly synthesized compounds were evaluated for their antitumor activity and some of them showed high inhibition activities. |
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