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Glycopolymers and Glyco‐nanoparticles in Biomolecular Recognition Processes and Vaccine Development
Authors:Rajesh Sunasee  Ravin Narain
Affiliation:1. Department of Chemistry, Brandon University, Brandon, MB R7A 6A9, Canada;2. Department of Chemical and Materials Engineering, University of Alberta, Alberta Glycomics Centre, Edmonton, AB T6G 2G6, Canada
Abstract:With advances in polymerization techniques as well as selective chemical modification of carbohydrates, glycopolymers and glyco‐nanoparticles are emerging as an important class of materials with tailored properties or novel nanotechnology‐based platforms for a number of applications. The field of the so‐called glyco‐nanotechnology is starting to show some promises for future clinical applications. Glyco‐nanoparticles, due to their versatile nature, could offer a platform for the design of carbohydrate‐based vaccines and possibly allow the development of new single‐dose vaccines in disease areas of unmet need. This paper surveys the emerging roles of carbohydrate‐based polymeric and nanomaterials for biomolecular recognition processes and vaccine development.
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Keywords:biomolecular recognition  glyco‐nanoparticles  glycopolymers  vaccines
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