A Facile One‐Pot Synthesis of Pyrrolo[1, 2‐a] Indoles by Intramolecular 1,3‐Dipolar Cycloaddition under Neat‐Microwave Irradiation |
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| Authors: | Subramanya Hegde Jayadevan Jayashankaran Atanu Ghosal T.S.R Prasanna Y. Shivaraj K. Mohana Raju |
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| Affiliation: | 1. Department of Chemistry, CMJ University, , Shillong, 793 003;2. Department of Chemistry, Government Science College, , Bangalore, 560 001;3. Department of Chemistry, Kalyani University, , Kolkota, India;4. Department of Polymer Science & Technology, S.K. University, , Anantapur, Andhra Pradesh, India |
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| Abstract: | A straightforward and general approach for the stereoselective synthesis of fused pyrrolo[1,2‐a] indoles frameworks from>intramolecular 1,3‐dipolar cycloaddition using N‐alkylated Baylis–Hillman derivatives is presented. It was found that the cycloaddition proceeded efficiently under microwave irradiation in solvent‐free condition to afford highly stereoselective cycloadducts in good yield. |
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