An Efficient Synthesis of Clopenta[b]pyrazolo[4,3‐f]quinolin‐9(3H)‐one Derivatives by Three‐component Reaction in Ionic Liquids |
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| Authors: | Mei‐Mei Zhang Ming‐Yue Yin Xiang‐Shan Wang |
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| Institution: | 1. Key Laboratory of Biotechnology on Medical Plant of Jiangsu Province, Jiangsu Normal University, , Xuzhou Jiangsu, 221116 People's Republic of China;2. School of Chemistry and Chemical Engineering, Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, Jiangsu Normal University, , Xuzhou Jiangsu, 221116 People's Republic of China |
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| Abstract: | A mild and efficient method for the synthesis of 10‐aryl‐6,7,8,10‐tetrahydrocyclopentab]pyrazolo4,3‐f]quinolin‐9(3H)‐one derivatives is described in high yields at 50°C in ionic liquids. The method involves a three‐component reaction of aromatic aldehyde 1H‐indazol‐5‐amine and cyclopentane‐1,3‐dione. |
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