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Synthesis of novel 2‐alkoxy(aralkoxy)‐4H‐[1,2,4]triazolo[1,5‐a]quinazolin‐5‐ones starting with dialkyl‐N‐cyanoimidocarbonates
Authors:Rashad Al‐Salahi  Detlef Geffken
Affiliation:1. Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia;2. Department of Chemistry, Institute of Pharmacy, Hamburg University, Hamburg 20146, Germany
Abstract:A novel series of 2‐alkoxy(aralkoxy)‐4H‐[1,2,4]triazolo[1,5‐a]quinazolines were synthesized employing N‐cyanoimidocarbonates and 2‐hydrazinobenzoic acid as building blocks. Chemical transformation of the inherent lactam moiety in the targeted 2‐alkoxy(aralkoxy)[1,2,4]triazolo[1,5‐a]quinazolines was offered access to a variety of derivatives. J. Heterocyclic Chem., (2011).
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