An efficient synthesis of pyrrolo[1,2‐a]quinazolin‐5(1H)‐one derivatives with the aid of low‐valent titanium reagent |
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| Authors: | Xuan Zhao Da‐Qing Shi |
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| Institution: | Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, People's Republic of China |
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| Abstract: | A short and facile synthesis of 2,3,3a,4‐tetrahydropyrrolo1,2‐a]quinazolin‐5(1H)‐ones and 2,3,3a,4‐tetrahydropyrrolo1,2‐a]quinazoline‐1,5‐diones in good yields via the novel reductive cyclization of 2‐nitrobenzamides with haloketones or 4‐oxopentanoic acid promoted by low‐valent titanium reagent is described. J. Heterocyclic Chem., (2011). |
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