Iron‐catalyzed tandem reactions of aldehydes,terminal alkynes,and primary amines as a strategy for the synthesis of quinoline derivatives |
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Authors: | Yicheng Zhang Pinhua Li Lei Wang |
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Institution: | 1. Department of Chemistry, Huaibei Normal University, Huaibei, Anhui 235000, People's Republic of China;2. State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, People's Republic of China |
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Abstract: | FeCl3‐catalyzed three‐component tandem condensation/addition/cyclization/oxidation reactions of aldehydes, terminal alkynes, and primary amines have been developed. The processes can provide a diverse range of quinoline derivatives in good yields from simple starting materials. A possible reaction mechanism was proposed. J. Heterocyclic Chem., (2010). |
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