Design and synthesis of new derivatives of 3H‐quinazolin‐4‐one as potential anticonvulsant agents |
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| Authors: | Uma Kabra Chandrabhan Chopde Sudhir Wadodkar |
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| Institution: | 1. Department of Pharmaceutical Chemistry, Shrimati Kishoritai Bhoyar College of Pharmacy, New Kamptee, Nagpur 441002, Maharashtra, India;2. Department of Pharmacology, Shrimati Kishoritai Bhoyar College of Pharmacy, New Kamptee, Nagpur 441002, Maharashtra, India |
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| Abstract: | As a part of systematic investigation on synthesis and biological activities, some new derivatives of 2‐ethyl‐3‐(substituted benzothiazole‐2′‐yl)–3H]‐quinazolin‐4‐ones 3 have been synthesized, and the structures of the compounds were confirmed by elemental analysis and spectral data. The newly synthesized derivatives are then screened for anticonvulsant activity by maximal electroshock method. J. Heterocyclic Chem., (2011). |
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