One‐pot synthesis of 2,3‐disubstituted‐2,3‐dihydroquinazolin‐4(1H)‐ones using [Hmim][NO3]: An eco‐friendly protocol |
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| Authors: | Iraj Mohammadpoor‐Baltork Ahmad Reza Khosropour Majid Moghadam Shahram Tangestaninejad Valiollah Mirkhani Mohammad Soltani Arsalan Mirjafari |
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| Institution: | Catalysis Division, Department of Chemistry, University of Isfahan, Isfahan 81746‐7344, Iran |
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| Abstract: | An efficient method for the synthesis of a series of 2,3‐disubstituted‐2,3‐dihydroquinazolin‐4(1H)‐ones is described via one‐pot condensation reaction of isatoic anhydride, aryl aldehydes, and primary amines using a Brønsted acidic ionic liquid, Hmim]NO3], as a catalyst and medium. The present protocol enjoys convenient reaction and simple work‐up, greenness, short reaction times, and reusable catalyst as well as mild reaction conditions. J. Heterocyclic Chem., (2011). |
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