Two New 23‐Membered Macrolactones from a Terrestrial Bacterium,Streptomyces sp. IMBJ01 |
| |
| Authors: | Fang‐Fang Qi Jing Li Shi‐Wei Sun Tian‐Jiao Zhu Wen‐Jun Mao Qian‐Qun Gu De‐Hai Li |
| |
| Institution: | 1. College of Marine Life Sciences, Ocean University of China, Qingdao 266003, P.?R. China;2. Key Laboratory of Marine Drugs, Chinese Ministry of Education, Institute of Marine Drugs and Food, Ocean University of China, Qingdao 266003, P.?R. China, (phone: +86‐532‐82031619;3. fax: +86‐532‐82033054) |
| |
| Abstract: | Two new unusual 23‐membered macrolactones, named griseoviridins B ( 1 ) and C ( 2 ), along with the known analogue griseoviridin ( 3 ) were isolated from the culture of Streptomyces sp. IMBJ01, a terrestrial bacterium isolated from Wolong, Sichuan Province, China. The structures of 1 and 2 were elucidated on the basis of extensive spectroscopic data and their absolute configurations were determined by comparison of their CD spectra with those of compound 3 . |
| |
| Keywords: | Streptomyces species Macrolactones Griseoviridins B and C Cytotoxic activity Antibiotic activity |
|
|
