Chloromethylation of 8-hydroxyquinoline |
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| Authors: | Quintus Fernando W.L.W. Ludekens K. Gnanasoorian |
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| Affiliation: | Department of Chemistry, University of Ceylon, Colombo Ceylon Italy |
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| Abstract: | The reaction of formaldehyde on a hydrochloric acid solution of 8-hydroxyquinoline, in the presence of hydrochloric acid gas, gave a chloromethyl derivative which is probably 7-chloromethyl-8-hydroxyquinoline hydrochloride. This compound is readily converted into the 7-hydroxymethyl derivative in alkaline solution. The 7-chloromethyl compound has been investigated as an analytical reagent for metal ions in acid solutions. |
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