Isoprenoids and Flavonoids with Antimicrobial Activity from Ficus conraui Warburg (Moraceae) |
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| Authors: | Rodrigue T. Kengap Gilbert D. W. F. Kapche Jean‐Paul Dzoyem Ingrid K. Simo Pantaleon Ambassa Louis P. Sandjo Berhanu M. Abegaz Bonaventure T. Ngadjui |
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| Affiliation: | 1. Department of Organic Chemistry, Faculty of Science, University of Yaoundé I, P.?O. Box 812, Yaoundé, Cameroon (phone: +237‐77‐605857;2. fax: +237‐22‐235396);3. Department of Chemistry, Higher Teachers' Training College, University of Yaoundé I, P.O. Box 47, Yaoundé, Cameroon (phone: +237‐77‐664973;4. Departments of Biochemistry, Faculty of Science, University of Dschang, P.O. Box 67, Dschang, Cameroon;5. Departments of Chemistry, Faculty of Science, University of Dschang, P.O. Box 67, Dschang, Cameroon;6. Department of Chemistry, Faculty of Science, University of Botswana, Private Bag 00704, Gaborone, Botswana |
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| Abstract: | A new triterpene, conrauidienol ( 1 ), and a new dihydroflavonol, conrauiflavonol ( 2 ), along with β‐amyrin acetate ( 3 ), betulinic acid ( 4 ), ursolic acid ( 5 ), 6β‐hydroxystigmasta‐4,22‐dien‐3‐one ( 6 ), 8‐prenylapigenin ( 7 ), β‐sitosterol glucoside ( 8 ), and 3,4′,5‐trihydroxy‐6″,6″‐dimethylpyrano[2,3‐g]flavone ( 9 ) were isolated from the stem barks of Ficus conraui Warburg (Moraceae). Their structures were elucidated by spectroscopic analysis. The hexane, AcOEt, and MeOH extracts, as well as the new isolated compounds exhibited selective antimicrobial activities varying from weak to moderate. |
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| Keywords: | Ficus conraui Triterpenes Conrauidienol Flavonol, dihydro‐ Conrauiflavonol Antimicrobial activity |
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