An expeditious one‐pot synthesis of substituted phenylazetidin‐2‐ones in the presence of zeolite |
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| Authors: | Ramakanth Pagadala Jyotsna S Meshram Himani N Chopde Venkateshwarlu Jetti V Udayini |
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| Institution: | 1. Department of Chemistry, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur 440 033, Maharashtra, India;2. Department of Botany, Osmania University, Hyderabad 500 007, Andhra Pradesh, India |
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| Abstract: | In this study, one‐pot rapid and efficient series of phenylazetidin‐2‐ones were synthesized from N,N‐dimethylaminobenzaldehyde, different substituted aromatic amines and phenylacetyl chloride in the presence of zeolite catalyst under microwave irradiation. We also reported schiff bases (1a–j) by classical and conventional microwave technique. The titled compounds are evaluated for their antimicrobial properties. The activities are due to C?O, C? N, linkages in 2‐azetidinones. All the compounds have shown comparable antibacterial activities. J. Heterocyclic Chem., (2011). |
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