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Meliarachins A–K: Eleven Limonoids from the Twigs and Leaves of Melia azedarach
Authors:Zu‐Shang Su  Sheng‐Ping Yang  Sheng Zhang  Lei Dong  Jian‐Min Yue
Institution:State Key Laboratory of Drug Research, Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 555 Zuchongzhi Road, Zhangjiang Hi‐Tech Park, Shanghai 201203, P.?R. China, (phone/fax: +86‐21‐50806718)
Abstract:Eleven new limonoids, meliarachins A–K ( 1 – 11 , resp.), together with five known ones, were isolated from the twigs and leaves of Melia azedarach. The structures of the new compounds were elucidated on the basis of spectroscopic analysis. Compounds 4 and 8 exhibited moderate antibacterial activities against Gram‐positive bacteria.
Keywords:Melia azedarach  Limonoids  Meliarachins A       K
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