Preparation of Silica Nanoparticles from Organic Laboratory Waste of Silica Gel HF254 and Their Use as a Highly Efficient Catalyst for the One‐Pot Synthesis of 2,3‐Dihydro‐1H‐isoindolone Derivatives |
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| Authors: | Ali Ramazani Amir Mahyari Azam Farshadi Morteza Rouhani |
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| Institution: | 1. Chemistry Department, Zanjan University, P.O. Box 45195‐313, Zanjan, Iran, (phone: +98‐241‐5152572;2. fax: +98‐241‐5152477);3. Young Researchers Club, Zanjan Branch, Islamic Azad University, Zanjan, Iran |
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| Abstract: | Reaction of an isocyanide with an iminium ion intermediate, formed by reaction between 6‐formyl‐2,3‐dimethoxybenzoic acid and secondary amines (dibenzyl‐ or benzyl(isopropyl)amine) in the presence of silica nanoparticles (silica NPs, ca. 70 nm) proceeds smoothly at room temperature to afford 2,3‐dihydro‐1H‐isoindolone derivatives in high yields. |
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| Keywords: | Silica nanoparticles Catalysis Isocyanide 1H‐Isoindolones 2 3‐dihydro‐ Multicomponent reactions Nanoparticles |
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