NaBH4‐I2 mediated chemoselective reduction of γ‐lactam and thio‐γ‐lactam in presence of gem‐dicarboxylates: An easy access to 1,3‐diaryl pyrrolidines |
| |
| Authors: | Gopa Barman Pranab Haldar Neelanjan Dutta Jayanta K Ray |
| |
| Institution: | Department of Chemistry, Indian Institute of Technology, Kharagpur 721302, India |
| |
| Abstract: | Substituted pyrrolidine derivatives were synthesized in high yield by NaBH4/I2 mediated chemoselective reduction of N‐aryl‐γ‐lactam and N‐aryl‐thio‐γ‐lactam‐2,2‐dicarboxylate. With excess NaBH4/I2, carbonyl functionality of the ester groups remained unchanged. J. Heterocyclic Chem., (2011). |
| |
| Keywords: | |
|
|
