Two New Cytotoxic Alkaloids from Mappianthus iodoides Hand.‐Mazz. |
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Authors: | Xi‐Bin Xiao Yue‐Xing Lin Geng‐Bo Xu Xu‐Bo Gong Ying Gu Jie‐Feng Tong Jing Yang |
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Affiliation: | 1. Department of Hematology, Second Affiliated Hospital, Zhejiang University, No.?88 Jiefang Road, Hangzhou 310009, P.?R. China (phone: +86‐571‐87783652);2. Blood Bank, Second Affiliated Hospital, Zhejiang University, Hangzhou 310009, P.?R. China |
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Abstract: | Two new alkaloids, mappine A ( 1 ) and mapposidic acid ( 2 ), together with eleven known compounds, were isolated from the stems of Mappianthus iodoides Hand.‐Mazz. Their structures were elucidated by means of spectroscopic and mass‐spectrometric analyses, particularly 1D‐ and 2D‐NMR spectroscopy. The cytotoxic activities of the two new alkaloids were also evaluated. |
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Keywords: | Mappianthus iodoides Alkaloids Mappine A Mapposidic acid Cytotoxic activity |
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