|
|||||
|
|
Facile Knoevenagel and Domino Knoevenagel/Michael Reactions Using Gel‐Entrapped Base Catalysts |
|
| Authors: | Shital Shinde Gajanan Rashinkar Arjun Kumbhar Santosh Kamble Rajashri Salunkhe |
| Affiliation: | 1. Department of Chemistry, Shivaji University, Kolhapur, 416004, M.S., India, (phone: +91?231?2609169;2. fax: +91?231?2692333) |
| Abstract: | An efficient method for Knoevenagel condensation of arenecarbaldehydes with active methylene compounds such as barbituric acid and Meldrum's acid in the presence of gel‐entrapped base catalysts is reported. The method has been extended to the one‐pot synthesis of arylmethylene‐bis[3‐hydroxycyclohex‐2‐en‐1‐one] derivatives from dimedone (=5,5‐dimethylcyclohexane‐1,3‐dione) and arenecarbaldehydes by using domino Knoevenagel/Michael reaction sequence. |
| Keywords: | Knoevenagel condensation Michael reaction Gel‐entrapped base catalysts Recyclability Methylene compounds Catalysis |