Synthesis and transformations of hydrazine substituted 6‐fluoro derivatives of 1,3,4‐thiadiazolo[3,2‐a]pyrimidine |
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| Authors: | Muhamadsho A Kukaniev Cyril Párkányi |
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| Institution: | 1. Laboratory of Heterocyclic Compounds, V.I.Nikitin Institute of Chemistry of the Academy of Sciences of the Republic of Tajikistan, 734063 Dushanbe, Tajikistan;2. Department of Chemistry and Biochemistry, Florida Atlantic University, Boca Raton, Florida 33431‐0991 |
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| Abstract: | 2‐Alkyl and 2‐arylhydrazine derivatives of 5H‐2‐R‐6‐fluoro‐7‐methyl‐1,3,4‐thiadiazolo3,2‐a]pyrimidin‐5‐one were prepared by reaction of 5H‐2‐bromo‐6‐fluoro‐7‐methyl‐1,3,4‐thiadiazolo3,2‐a]pyrimidin‐5‐one with hydrazine derivatives. A convenient procedure was developed for the preparation of new hydrazine derivatives of 5H‐2‐R‐6‐fluoro‐7‐methyl‐1,3,4‐thiadiazolo3,2‐a]pyrimidin‐5‐one. J. Heterocyclic Chem., (2011). |
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