Metal‐Free Multicomponent Synthesis of (α‐Aminoalkyl)phosphonates Using 2,4,6‐Trichloro‐1,3,5‐triazine |
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| Authors: | Biswanath Das Avula Satya Kumar Jayprakash Narayan Kumar |
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| Institution: | 1. Organic Chemistry Division‐I, Indian Institute of Chemical Technology, Hyderabad‐500?007, India, (phone: +91‐40‐7193434;2. fax: +91‐40‐7160512) |
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| Abstract: | (α‐Aminoalkyl)phosphonates have efficiently been synthesized by multicomponent reaction of aldehydes, amines, and triethyl phosphite in the presence of 2,4,6‐trichloro‐1,3,5‐triazine at room temperature. The products are formed in high yields (83–91%) within 0.5–1 h. |
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| Keywords: | Multicomponent reactions Phosphonates (α ‐aminoalkyl)‐ |
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