Streptomycindole,an Indole Alkaloid from a Marine Streptomyces sp. DA22 Associated with South China Sea Sponge Craniella australiensis |
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Authors: | Xiao‐Li Huang Yao Gao Duo‐Qing Xue Hai‐Li Liu Chong‐Sheng Peng Feng‐Li Zhang Zhi‐Yong Li Yue‐Wei Guo |
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Institution: | 1. Key Laboratory of Microbial Metabolism, Ministry of Education, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240,?P.?R. China, (phone: +86‐21‐3420‐4036);2. State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, P.?R. China (phone: +86‐21‐50805813);3. School of Pharmacy, Shanghai Jiao Tong University, Shanghai, P.?R. China |
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Abstract: | A new indole alkaloid, streptomycindole ( 1 ), and a known related compound, N‐phenylacetyl‐L ‐tryptophan ( 2 ), have been isolated from Streptomyces sp. DA22, associated with South China Sea sponge Craniella australiensis. Their structures were established on the basis of a combination of mass spectrometry, 1H‐ and 13C‐NMR spectroscopic analyses, and chemical methods. |
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Keywords: | Streptomycindole Alkaloids Indole alkaloids Streptomyces species Craniella australiensis |
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