Solvent‐free three‐component synthesis of 7‐aryl‐1,1‐dioxothieno[3,2‐b]pyran derivatives catalyzed by ammonium acetate |
| |
| Authors: | Changsheng Yao Xiaodong Feng Cuihua Wang Bei Jiang Chenxia Yu Xiangshan Wang Tuanjie Li Shujiang Tu |
| |
| Affiliation: | School of Chemistry and Chemical Engineering, Key Laboratory of Biotechnology on Medical Plant, Xuzhou Normal University, Xuzhou, Jiangsu 221116, People's Republic of China |
| |
| Abstract: | An efficient synthesis of 7‐aryl‐1,1‐dioxothieno[3,2‐b]pyran derivatives via the reaction of aryl aldehyde, tetrahydrothiophene‐3‐one‐1,1‐dioxide and malononitrile or ethyl 2‐cyanoacetate was performed at room temperature catalyzed by ammonium acetate under solvent‐free conditions. Compared with the conventional methods, this protocol features mild reaction conditions, high yields, and eco‐friendliness. J. Heterocyclic Chem., (2011). |
| |
| Keywords: | |
|
|
