Chemoselective synthesis of 4‐oxo‐2‐aryl‐4,10‐dihydropyrimido [1,2‐a][1,3]benzimidazol‐3‐yl cyanides via [3+3] atom combination of 2‐aminobenzimidazole with ethyl‐α‐cyanocinnamoates |
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| Authors: | Hassan Sheibani Fahimeh Hassani |
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| Affiliation: | Department of Chemistry, Shahid Bahonar University of Kerman, Kerman 76169, Iran |
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| Abstract: | Chemoselective synthesis of 4‐oxo‐2‐aryl‐4,10‐dihydropyrimido[1,2‐a][1,3]benzimidazol‐3‐yl cyanides from three‐component reactions of 2‐aminobenzimidazole, aldehydes, and ethyl cyanoacetate via [3+3] atom combination is reported. The effect of different base catalysts such as sodium acetate, triethylamine, and magnesium oxide MgO on the product yield has also been investigated under conventional heating. J. Heterocyclic Chem., (2011). |
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