A Short and Efficient Synthesis of a Novel Diarylheptanoid Isolated from Pleuranthodium Racemigerum

The first total synthesis of the linear diarylheptanoid 1‐(4″‐methoxyphenyl)‐7‐(4′‐hydroxyphenyl)‐(E)‐hept‐2‐ene, which has a uniquely nonconjugated olefin, was achieved. The synthetic route employed an olefin cross‐metathesis as a key step. Beginning with commercially available 3‐(4‐hydroxyphenyl)propan‐1‐ol, the final product was made in three steps with a 52% yield.