Chemical constituents from the leaves of Manglietia phuthoensis and their effects on osteoblastic MC3T3-E1 cells |
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| Authors: | Kiem Phan Van Tri Mai Dinh Tuong Le Vo Dinh Tung Nguyen Huu Hanh Nguyen Ngoc Quang Tran Hong Cuong Nguyen Xuan Minh Chau Van Choi Eun-Mi Kim Young Ho |
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| Affiliation: | Institute of Natural Products Chemistry, Vietnamese Academy of Science and Technology, Viet, Nghiado, Caugiay, Hanoi, Vietnam. |
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| Abstract: | Two new phenyl glycosides, mangliesides A and B (1, 2), a new ionol glycoside, manglieside C (3), two new lignan glycosides, mangliesides D and E (4, 5), were isolated from the leaves of Manglietia phuthoensis, along with two known lignans, 3-methoxymagnolol (6) and obovatol (7). Their structures were established by means of 1D and 2D NMR, electrospray ionization (ESI)-MS and HR-ESI-MS experiments. Among them, compounds 2 and 5 significantly (p<0.05) increased the growth and differentiation of osteoblastic MC3T3-E1 cells in vitro. |
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