Improved TLC systems for rapid resolution of phenyl thiohydantoin amino acids |
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| Authors: | R Bhushan V K Mahesh P V Mallikharjun |
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| Affiliation: | Department of Chemistry, University of Roorkee, India. |
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| Abstract: | Two new solvent systems, n-hexane + propionic acid (26:5, v/v) and chloroform + acetone (29:3, v/v), for the rapid resolution and identification of an 18-component mixture of phenylthiohydantoin amino acids are reported. Using these systems certain difficult combinations of phenylthiohydantoin amino acids are resolved. Two more solvent systems, viz chloroform + acetic acid (27:3, v/v) and chloroform + methanol (30:4, v/v), are developed to resolve phenylthiodantoin derivatives of aspartic and glutamic acids. |
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