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Synthesis and DNA Cleavage Studies of 2,6-Dimethoxyhydroquinone-3-Mercaptoacetic Acid Conjugates
引用本文:Yu Fei SONG,Pin YANG* Institute of Molecular Science,Shanxi University,Taiyuan 030006. Synthesis and DNA Cleavage Studies of 2,6-Dimethoxyhydroquinone-3-Mercaptoacetic Acid Conjugates[J]. 中国化学快报, 2001, 0(8)
作者姓名:Yu Fei SONG  Pin YANG* Institute of Molecular Science  Shanxi University  Taiyuan 030006
作者单位:Yu Fei SONG,Pin YANG* Institute of Molecular Science,Shanxi University,Taiyuan 030006
摘    要:In previous paper and work, we reported the synthesis and cytotoxicity studies of a novel series of short chain peptide conjugates of the cytotoxic agent 2, 6-dimethoxyhydro -quinone-3-mercaptoacetic acid1 (DMQ-MA). The DMQ-MA is a derivative of 2,6-dimethoxybenzoquinone, which is a natural product of fermented wheat germ and found to have a wide spectrum of cytotoxicity against various tumor cell lines under the synergistic activation of L-ascorbic acid (AH2)2,3. Compared with DMQ, DMQ…


Synthesis and DNA Cleavage Studies of 2,6-Dimethoxyhydroquinone-3-Mercaptoacetic Acid Conjugates
Yu Fei SONG,Pin YANG Institute of Molecular Science,Shanxi University,Taiyuan. Synthesis and DNA Cleavage Studies of 2,6-Dimethoxyhydroquinone-3-Mercaptoacetic Acid Conjugates[J]. Chinese Chemical Letters, 2001, 0(8)
Authors:Yu Fei SONG  Pin YANG Institute of Molecular Science  Shanxi University  Taiyuan
Affiliation:Yu Fei SONG,Pin YANG* Institute of Molecular Science,Shanxi University,Taiyuan 030006
Abstract:
Keywords:2  6-Dimethoxyhydroquinone-3-mercaptoacetic acid   tripeptide   cleavage   pBR322 DNA.
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