Nebenprodukt bei der Herstellung von 4-Hydroxy-3-phenylcumarin |
| |
| Authors: | Wolfgang Stadlbauer Thomas Kappe |
| |
| Institution: | (1) Institut für Organische Chemie, Universität Graz, A-8010 Graz, Österreich |
| |
| Abstract: | The synthesis of 4-hydroxy-3-phenylcoumarin (3a) from phenol (1) and diethylphenylmalonate (2) yields the isocoumarin derivative4 as a by-product (1–2%). If3a is heated with2 or diphenylcarbonate (6) at 300°C the coumarino-isocoumarin4 is formed in 83% and 85% yield, respectively. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
