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Baker’s yeast catalyzed one-pot three-component synthesis of polyfunctionalized 4H-pyrans
Authors:Umesh R. PratapDhanaji V. Jawale  Prashant D. NetankarRamrao A. Mane
Affiliation:Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad 431 004, India
Abstract:Baker’s yeast catalyzed one-pot three-component cyclocondensation of aryl aldehydes, malononitrile, and β-dicarbonyls in organic medium has been carried out to obtain polyfunctionalized 4H-pyrans. The reaction has been carried out at room temperature in organic solvent, dimethylacetamide and the products obtained in good to moderate yields with simple work up procedure.
Keywords:Baker&rsquo  s yeast   4H-Pyran   Cyclocondensation   Biocatalysis   One-pot
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