Tin-free generation of alkyl radicals from alkyl 4-pentynyl sulfides via homolytic substitution at the sulfur atom |
| |
Authors: | Bencivenni Giorgio Lanza Tommaso Leardini Rino Minozzi Matteo Nanni Daniele Spagnolo Piero Zanardi Giuseppe |
| |
Institution: | Dipartimento di Chimica Organica A. Mangini, Università di Bologna, Viale Risorgimento 4, I-40136 Bologna, Italy. |
| |
Abstract: | Homolytic substitution at the sulfur atom of beta-(phenylsulfanyl)vinyl radicals, obtained by radical reaction of benzenethiol with easily accessible alkyl 4-pentynyl sulfides, is a mild, effective, tin-free route for the generation of all types of alkyl radicals. This protocol can be employed in reductive defunctionalizations as well as cyclizations onto both electron-rich and electron-poor C-C double bonds. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|