Synthesis and properties of substituted 2-imidazolidinones

4-Hydroxy- and 4-hydroxylamino-1-hydroxy-3-aryl-5,5-dimethyl-2-imidazolidinones, respectively, were obtained by treatment of N-arylcarbamoyl derivatives of N-(1-oximino-2-methyl-2-porpyl)hydroxylamine with acids and alkalis. 4-Hydroxylaminoimidazolidinones react with p-nitrobenzaldehyde to give nitrones and are converted in acidic media to 4-hydroxy derivatives, which by the action of methanol in the presence of p-toluenesulfonic acid give 4-methoxy-2-imidazolidinones. Acylation and alkylation of 4-hydroxy- and 4-methoxy-2-imidazolidinones take place at the hydroxy group attached to N(₁).Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1255–1261, September, 1976.