Microwave-assisted synthesis of substituted hexahydro-pyrrolo[3,2-c]quinolines |
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| Authors: | Neuschl Michal Bogdal Darek Potacek Milan |
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| Affiliation: | Department of Organic Chemistry, Masaryk University, Kotlarska 2, Brno, Czech Republic. |
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| Abstract: | New compounds with the ethyl hexahydro-1H-pyrrolo[3,2-c]quinoline-2-carboxylate skeleton were prepared by microwave-assisted intramolecular 1,3-dipolar cycloaddition reactions. The reactions were carried out under solvent-free conditions and compared with the same reaction in the presence of a solvent and a catalyst. Steric effects on the selectivity of the reaction were noted and evaluated. |
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