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Spray Pyrolysis Preparation of Apatite-Composite Particles for Biological Application |
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| Authors: | Akiyoshi Osaka Kanji Tsuru H Iida Chikara Ohtsuki Satoshi Hayakawa Yoshinari Miura |
| Institution: | (1) Department of Bioengineering Science, Faculty of Engineering, Okayama University, 700 Tsushima Okayama-shi, Japan;(2) Department of Environmental Chemistry and Materials, Faculty of Environmental Science and Technology, Okayama University, 700 Tsushima, Okayama-shi, Japan |
| Abstract: | Apatite derived by sol-gel routes through an amorphous state or derived biomimetically is likely to provide chemically and biologically active surfaces. Thus apatite or apatite-composite particles were prepared by spray-pyrolysis of several solutions as they were applicable to medical treatment. Calcium lactate and ammonium dihydrogen phosphate aqueous solutions stabilized with ethylenediaminetetraacetic acid were sprayed ultrasonically and pyrolysed at 600°C to yield amorphous particles of apatite while apatite-ferric oxide composite powders were prepared from the solutions of calcium lactate and ferric nitrate. Solutions of calcium nitrate and titanium ethoxide in 0.5 N HNO3 were also spray-pyrolysed at 600°C to prepare calcium titanate and titanium oxide particles trapped on a Ti substrate. Apatite could biomimetically be developed on the calcium titanate particles when they were soaked in an acellular simulated body fluid. |
| Keywords: | spray pyrolysis apatite composite particle biomimetic deposition |
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